O-benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine
fmoc-O-benzyl-L-threonine
CAS: 117872-75-0
Molecular Formula: C26H25NO5
O-benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine - Names and Identifiers
| Name | fmoc-O-benzyl-L-threonine |
| Synonyms | FMOC-THR(BZL)-OH Fmoc-Thr9Bzl0-OH Fmoc-Thr(Bzl)-OH Fmoc-THr(Bzl)-OH FMOC-THREONINE(BZL)-OH fmoc-O-benzyl-L-threonine N-A-FMOC-O-BENZYL-L-THREONINE N-ALPHA-FMOC-O-BENZYL-L-THREONINE Fmoc-O-benzyl-L-threonine,Fmoc-Thr(Bzl) N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-BENZYL-L-THREONINE O-benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-BENZYL-L-THREONINE |
| CAS | 117872-75-0 |
| InChI | InChI=1/C26H25NO5/c1-17(31-15-18-9-3-2-4-10-18)24(25(28)29)27-26(30)32-16-23-21-13-7-5-11-19(21)20-12-6-8-14-22(20)23/h2-14,17,23-24H,15-16H2,1H3,(H,27,30)(H,28,29)/t17-,24+/m1/s1 |
O-benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine - Physico-chemical Properties
| Molecular Formula | C26H25NO5 |
| Molar Mass | 431.48 |
| Density | 1.257±0.06 g/cm3(Predicted) |
| Boling Point | 643.7±55.0 °C(Predicted) |
| Flash Point | 343.1°C |
| Vapor Presure | 1.89E-17mmHg at 25°C |
| Appearance | White powder |
| Color | White |
| BRN | 6353662 |
| pKa | 3.39±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.612 |
| MDL | MFCD00077073 |
O-benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
O-benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine - Introduction
Fluorenylmethoxycarbonyl-O-benzyl-L-threonine is an organic compound. Its structure consists of a benzene ring, a benzyl group, a carboxyl group, a methoxy group, and a threonine residue.
The compound is commonly used in various activating reagents in organic synthesis reactions. It has good chemical stability and can react with other compounds to generate compounds such as esters or amides. Because it has the structure of benzene ring and benzyl group, it can also be used in organic photoelectric materials and organic electronic devices.
The preparation of fluorenylmethoxycarbonyl-O-benzyl-L-threonine can be carried out by a chemical synthesis method. A commonly used method is to first carboxyl-protected fluorenecinol and then react with benzylic acid to produce fluorenylmethoxycarbonyl-O-benzoyl chloride. The fluorenylmethoxycarbonyl-O-benzoyl chloride is then reacted with L-threonine to produce the final product.
Regarding safety information, there is currently no clear report on fluorenylmethoxycarbonyl-O-benzyl-L-threonine. However, because it is a reagent in organic synthesis, it is necessary to follow laboratory safety regulations and pay attention to protective measures during operation to ensure the safety of operators. Personal protective equipment such as gloves, goggles and protective jackets should be used if necessary. Also, avoid contact with the skin, inhalation of gas or ingestion of the compound. It is best to read the safety instructions of the relevant chemicals before use and operate under the guidance of an experienced person.
The compound is commonly used in various activating reagents in organic synthesis reactions. It has good chemical stability and can react with other compounds to generate compounds such as esters or amides. Because it has the structure of benzene ring and benzyl group, it can also be used in organic photoelectric materials and organic electronic devices.
The preparation of fluorenylmethoxycarbonyl-O-benzyl-L-threonine can be carried out by a chemical synthesis method. A commonly used method is to first carboxyl-protected fluorenecinol and then react with benzylic acid to produce fluorenylmethoxycarbonyl-O-benzoyl chloride. The fluorenylmethoxycarbonyl-O-benzoyl chloride is then reacted with L-threonine to produce the final product.
Regarding safety information, there is currently no clear report on fluorenylmethoxycarbonyl-O-benzyl-L-threonine. However, because it is a reagent in organic synthesis, it is necessary to follow laboratory safety regulations and pay attention to protective measures during operation to ensure the safety of operators. Personal protective equipment such as gloves, goggles and protective jackets should be used if necessary. Also, avoid contact with the skin, inhalation of gas or ingestion of the compound. It is best to read the safety instructions of the relevant chemicals before use and operate under the guidance of an experienced person.
Last Update：2024-04-09 21:32:37
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